ABSTRACT

Year : 2022  |  Volume : 6  |  Issue : 2  |  Page : 76

Stroke Rehabilitation: AB No: 148: Therapeutic effect of Multi-target non-invasive Cortical Stimulation on Cognitive, Motor Domains and Gait in Sub acute Stroke Survivors- Case Series

Divya Midha, Narkeesh Arumugam
Punjabi University, Patiala, Punjab, India

Correspondence Address:

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2456-7787.361080

Background: The optimum recovery in a stroke individual cannot be expected by ignoring the impact of simultaneous cognitive deficits. Identification of involved networks in a patient-specific context along with the deeper understanding of interconnected neuronal network may yield better outcomes when applied with conventional rehabilitation. Aim: Therapeutic effect of multitarget cortical stimulation on cognitive domains, motor functions of paretic hand and gait in subacute stroke survivors. Methodology: Study was randomized sham controlled, parallel Groups trial registered with the clinical trial registry of India (CTRI/2020/01/022998). A total of 06 Sub- acute Stroke patients were randomly allocated to both the groups. Intervention: Experimental group participants received Multichannel Transcranial Direct current stimulation (M-tDCS) over the primary motor cortex i.e. C3/C4 point and dorsolateral prefrontal cortex i.e. F3/f4 point with 1.2 mA intensity for 20 minutes. SaeboFlex-assisted training, functional electrical stimulation over the lower extremity and conventional physiotherapy rehabilitation for 5 sessions/week for total 4 weeks. Control group received sham M-tDCS in which stimulation was ramped off to zero after 30 seconds of stimulation. Outcome Measures.EEG Fugl-Meyer assessment scale for the upper and lower extremity, Wisconsin Gait Scale and the Stroke Specific Quality of Life measures. Assessment was taken at Day 0, 15 and 30 post interventions. Results: Experimental group: Mean and Standard deviation scores FMA-UE varied from 67.00±5.56 to 93.00±2.64. FMA-LE from 57.00±10.14 to 74.67±12.66. NHPT from 257.33±48.38 to 167.33±41.48, WGS from 38.41±2.63 to 30.98±1.51, SSQOL from 87.00±12.53 to 136.00±12.66 on Day 0 and Day 30 respectively. Control Group scores FMA-UE varied from 77.66±11.50 to 108.00±4.00, FMA-LE from 66.33±4.50 to 82.33±7.09, NHPT from 178.00±9.16 to 152.00±3.46, WGS from 34.78±4.27 to 28.08±1.51, SSQOL from 105.30±6.11 to 159.67±16.8. Conclusion: Application of M-tDCS induced improvements in motor functions of the UE and LE, gait parameters with significant improvement in overall quality of life.

Keywords: Stroke, Non Invasive Brain stimulation, Multichannel Trans-cranial Direct current stimulation